hepaticFibrosis相关论文
目的:本实验旨在进一步验证与评价M2BP与M2BPGi在胆道闭锁（biliary atresia，BA）患儿肝纤维化中的作用。方法:收集2019年9月至2020年11......
目的:评估肝脏瞬时弹性成像、天冬氨酸转氨酶与血小板比值指数（APRI）及基于4因子的肝纤维化指数（FIB-4）对儿童非酒精性脂肪性肝病（NAFLD......
Indole-3-propionic Acid-aggravated CCl4-induced Liver Fibrosis via the TGF-β1/Smads Signaling Pathwa
Background and Aims: The pathogenesis of liver fibrosis involves liver damage, inflammation, oxidative stress, and intes......
Effects of Ganfukang（肝复康） on Expression of Connective Tissue Growth Factor and Focal Adhesion Kinase
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Hepatic fibrosis is a common feature of almost all chronic liver diseases. Formation of new vessels (angiogenesis) is a ......
Balancing Effect of Biejiajian Oral Liquid（鳖甲煎口服液） on ACE-Ang Ⅱ-AT1R Axis and ACE2-Ang-(1-7)-Mas Axi
Objective:To explore the effect of Biejiajian Oral liquid(鳖甲煎口服液, BOL) on CCI4-induced hepatic fibrosis in rats by......
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Aim: To investigate the distribution and function of α1-adenoreceptor subtypes (α1-AR) in rat hepatic stellate cells (......
Increased serum miR-1273g-3p levels are associated with chronic hepatitis C virus(HCV)-induced fibro
Objective(s): To determine whether serum levels of differentially expressed microRNAs(miRNAs)correlate with fibrosis in ......
Platycodon grandiflorum (Jacq.) A.DC.and Panax Ginseng C.A.mey extracts inhibits hepatic fibrosis in
Fibrosis is a phenomenon of fibrous connective tissue increase in the organs.Activated hepatic stellate cells(HSCs) are ......
Aldosterone induced liver sinusoidal endothelial cell capillarization and hepatic fibrosis via oxida
AIMS: Caveolin-1(Cav-1)is a anchoring protein which binds endothelial nitric oxide synthase(eNOS)and interacts with mine......
Betulinic acid exerts anti-fibrosis activity via regulating TLR4/NF-κB signaling and induces the apo
OBJECTIVE The purpose of the study was to investigate the anti-fibrosis mechanism of betulinic acid (BA), an active comp......
Plumbagin Ameliorates CCl4-induced Hepatic Fibrosis in Rats via the Epidermal Growth Factor Receptor
Objective Epidermal growth factor(EGF)and its signaling molecules — EGFreceptor(EGFR)and signal transducer and activato......
Objective: LXs are a class of newly found arachidonic acid metabolites, possess potent anti-inflammatory and proresoluti......
Background:Liuweiwuling(LWWL)tablets are an herbal product that exert remarkable effects on liver protection and aminotr......
Assessment of hepatic fibrosis by shear wave elastography in patients with liver tumors:A prospectiv
So far,it has been difficult to assess liver stiffness before surgery without performing a traditional liver biopsy.This......
Poria cocos extract inhibited the activation of hepatic stellate cells possibly via NFκB and PPARγ p
Aim: Activation of hepatic stellate cells (HSCs) plays a key role in hepatic fibrosis and chronic liver diseases.In this......
Aim: Thymoquinone (TQ) is the main active ingredient from the seeds of Nigella sativa Linn, which has been traditionally......
Salvianolic acid A prevents the pathological progress of hepatic fibrosis in rats with type 2 diabet
AIM The aim of the present study was to evaluate the effect of salvianolie acid A (SalA) on the pathological progression......
Effects of Compound Astragalus and Salvia Miltiorrhiza Extract on the Development of Hepatic Fibrosi
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The miR-23b/27b cluster balances BMP-7 and TGF-β signalings to suppress HSCs activation through down
Imbalance of the TGF-β and BMP-7 signaling pathways is a critical step in promoting hepatic stellate cell (HSC) activat......
Assessment of hepatic fibrosis by shear wave elastography in patients with liver malignancy:A prospe
Purpose:To evaluate the diagnostic performance of two-dimensional shear-wave elastography(SWE)for staging hepatic fibros......
Aim: Toinvestigate the protective effect of total glucosides ofYupingfeng (YTG) on hepatic fibrosis induced by carbon te......
Aims: To investigate the effects of Compound Astragalus and Salvia Miltiorrhiza Extract (CASE) on the hepatocarcinogenes......
Ligustrazine-induced apoptosis is involved in its regulation of expression of Bcl-2 and Bax by caspa
Aims: Accumulating experimental and clinical studies provide clear evidence for reversibility of hepatic fibrosis (HF).A......
The miR-23b/27b Cluster balances BMP-7 and TGF-β signalings to suppress Hepatic Stellate Cell Activa
Imbalance of the TGF-β and BMP-7 signaling pathways is a critical step in promoting hepatic stellate cell (HSC) activat......
Autophagy is a process of lysosome degradation, which plays an important role in maintaining cell homeostasis and organ ......
Comparison of Magnetic Resonance Elastography and Diffusion-weighted Imaging for Staging Hepatic Fib
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Effects of insulin-like growth factor binding protein-related protein 1 in mice with hepatic fibrosi
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目的了解瞬时弹性成像(TE)在评估慢性肝病儿童肝纤维化程度中的应用。方法纳入2017年1月至9月在复旦大学附属儿科医院同时进行TE和......
OBJECTIVE: The aim of this study was to observe the effect of oxymatrine on preventing hepatic fibrosis in rats and ......
Nonalcoholic fatty liver disease(NAFLD),a progressive disease that begins with simple steatosis,may develop to nonal......
目的探讨Hedgehog信号通路和上皮-间充质转化(epithelial-mesenchymal transition, EMT)在胆道闭锁(biliary atresia, BA)肝纤维化......
观察维吾尔药小茴香对实验性大鼠肝纤维化转化生长因子-β1（TGF-β11）的影响，探讨其抗肝纤维化作用及其机制。选取健康WisIar大鼠48只......
Effects of ultrasound-microbubble-mediated HGF transfer on hepatic structure and ultrastructure in h
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Hepatic fibrosis(HF)is the common pathological basis of all chronic liver diseases,and is a necessary stage for the deve......
目的 研究在成纤维细胞NIH-3T3中IL-13可溶性受体sIL-13Rα2对IL-13的抑制作用,为进一步研究sIL-13Rα2对日本血吸虫感染小鼠体内......
目前，对于树突状细胞（ DCs）的研究一般集中于骨髓来源的DCs、脾脏 DCs及外周血DCs的形态学和免疫学特性。肝脏是人体内的重要免疫器官......
目的探讨血吸虫病肝纤维化显微结构与超微结构的病理改变。方法在浙江省衢州市人民医院内科，选择2003年1月至2009年1月收治的9例血......
目的观察重组华支睾吸虫铁重链蛋白（CsFHC）对人肝星状细胞LX-2（简称LX-2细胞）的作用。方法采用细胞培养方法，体外培养LX-2细胞，采用细胞......
胆道闭锁是一种影响肝内、外胆管，伴随进行性肝组织纤维化导致不可逆的严重肝胆系统疾病。近期研究发现，Notch信号通路在哺乳类动物......
Objective To evaluate the effect of simple method and the composite method of carbon tetrachloride (CCl4) in establishme......
胆道闭锁(biliary atresia，BA)是胚胎期或新生儿期累及肝内外胆管的一种进行性病变。多数BA呈散发、进行性发展，与病毒感染破坏胆管......
